I graduated as a medical doctor in 1991 and had 5 years of postgraduate clinical training in internal medicine in China. Subsequently I acquired my Ph.D from Chinese Academy of Science, Shanghai Branch and started me research career in Singapore on dopamine (DA) neuron degeneration in Parkinson's disease (PD). Later I joined the National Neuroscience Institute (NNI) as a member of the Singapore National PD Translational Bench to Bedside team and continue to work on DA neuron degeneration in PD. Currently, I am an Associate principle investigator in Translational Therapeutics Laboratory of NNI and an Assistant Professor at Duke-NUS, NBD as well as a PI of NMRC and SHF grants. My interests lie in identification and verification of novel key molecular targets, signaling pathways or neuro-protective agents relevant to pathogenesis and therapy of debilitating human neurodegenerative diseases, including PD, Alzheimer’s disease (AD) and multiple sclerosis.

Molecular pathogenesis and therapy of neurodegenerative disease