Ischemia restricts the blood supply to the tissues due to damage or dysfunction of tissue causing shortage of oxygen which is needed for cellular metabolism. If damage occurs to the cardiac muscle it is called as Myocardial Ischemia or Cardiac Ischemia. It reduces the blood flow to the heart by partial or complete blockade of coronary arteries. It is an irreversible myocardial injury resulting in necrosis of significant portion of myocardium. This is usually caused by the build up of plaque, coronary artery disease, coronary artery spasm. Most common symptom of myocardial ischemia is angina which is also known as angina pectoris. Additional symptoms include sweating, fast heartbeat, shortness of breath, nausea. Treatment improves the blood flow to heart muscle it includes medication, angioplasty, surgery like stent, coronary artery bypass surgery. Myocardial ischemia leads to serious complications like heart attack, Irregular heartbeat and heart failure.