Ventricular septal defect is generally referred as hole in the heart. It is an abnormal opening between the ventricular septum. Ventricular septum is a wall which divides left and right ventricles of the heart. The hole may vary in size from pin to complete absence of ventricular septum. It is most often seen at birth but it occurs in adults after surgery and heart attack. It is detected by cardiac auscultation. Symptoms of ventricular septal defect are bluish skin, poor feeding and weight gain, fast breathing etc. Additional symptoms include failure to thrive, easy tiring. The symptoms are treated with drugs. Most of the openings are closed by their own but in many cases people need surgery. The surgery involves a catheter based procedure to close the hole. Complications of ventricular septal defect are heart failure, pulmonary hypertension, endocarditis, abnormal heart rhythms, and valve problems.