Biomarkers in the field of oncology brought a revolution in the delivering the precision medicine. Primary a biomarker is a kind of biological factor that advices the certain health conditions in a measurable way as it provides with the idea and the concept of genetic makeup of a person or in a certain disease condition. In the case of disease treatments, the biomarkers will help the doctors to understand the bodily response to the treatment and immune interactions for the certain disease treatment. The best examples of the biomarkers can be served by the hormones, genes, molecules like DNA. Specifically, the bio markers in cancer can be more definite and abundant sometimes generated as a response to the cancer treatment and can be found in stool, blood, bodily fluids, tumour tissues and many. The cancer biomarkers assist before, during and after treatments in cancer. The pre treatment cancer biomarkers are classified as three types. They are diagnostic- for diagnosis the type of cancer like the levels of PSA in prostate cancer., prognostic- to understand the perspective of cancer like BRAC1, BRAC2 and predictive bio markers- to understand the treatment approach for the specified human immune system and projection of any possible side effects like HER2 activation, KRAS activation. The other types of biomarkers used during and after the treatment such as short term monitoring to understand whether the treatment is working or any possible shown f side effects, the other type of biomarkers for the extended monitoring to understand the suppression of the cancer and to understand any re-progression of cancer.